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POSITIVE RESULTS

Nutrafol study links its supplement to 19%-37% faster hair growth in women

A peer-reviewed 180-woman study found Nutrafol's Hair Growth Nutraceuticals associated with faster linear hair growth at 6 months, an endpoint rarely measured in hair-thinning research.

Trial NCT06376409

Executive Summary

  • A completed study behind Nutrafol's flagship hair-growth nutraceuticals found a statistically significant increase in how fast hair grows over six months, alongside gains in hair count and scalp coverage.
  • The study measured an endpoint that is technically difficult to capture and rarely reported in hair-thinning research, giving the finding more specificity than typical self-reported hair counts, though the single-arm design means the comparison is each participant against her own starting point, not against a placebo or competing product.
  • The finding lands in a category with no validated disease-modifying drug therapy and dominated by other nutraceutical and topical entrants competing on similar subjective and objective hair measures.
  • Because the trial is non-registrational and carries no regulatory pathway, the study's value is scientific and marketing evidence for an already-commercial product rather than a catalyst that changes an approval or competitive-approval timeline.

The publication

Nutrafol announced on July 15, 2026 that a six-month, prospective, open-label, randomized study of its Hair Growth Nutraceuticals had been published in the peer-reviewed journal Dermatology and Therapy. The study enrolled 180 women between 18 and 70 years old with self-perceived thinning hair confirmed by a dermatologist, drawn from a trial registered as NCT06376409. Participants used one of several formulations tailored to different life stages, including menopause and postpartum. The trial's registered primary endpoint was the percent change in hair growth rate at Day 180 relative to baseline. New+1New Peer-Reviewed Study Published in Dermatology and Therapy Adds to Clinical Evidence Showing Nutrafol Hair Growth Nutraceuticals Improve Hair Growth in WomenJul 15, 2026Prospective Study of Nutraceutical Supplements to Support Hair Growth in FemalesNCT06376409

Probability of SuccessBased on the AppliedXL Probability of Success model. For more information about the methodology, read the research here.

Endpoint Met49%
Completes97%
Clinical Significance4%
Regulatory92%

How it was done

The design was open-label with a single experimental arm and no placebo or active comparator, drawing on 15 registered secondary endpoints spanning anagen-to-telogen ratio, total hair count, terminal and vellus hair counts, hair width per square centimeter, and subjective Consumer Perception Questionnaire scores at 90 and 180 days. Because there is no control arm, the reported changes are measured against each participant's own Day 0 baseline rather than against an untreated or comparator group. NCT06376409Prospective Study of Nutraceutical Supplements to Support Hair Growth in FemalesNCT06376409

The result

At six months, participants showed linear hair growth rates 19% to 37% faster than baseline, a statistically significant difference (p<0.001). The study also found statistically significant increases in anagen (actively growing) hairs across all study groups, and confirmed earlier findings on total hair count, terminal hair count, and scalp coverage. Dr. Raja Sivamani, the study's principal investigator, said measuring linear hair growth rate is uncommon in hair research because it requires validated equipment that many studies don't use or report, calling the finding one that "should shift how the field evaluates approaches to assess hair thinning and hair health". The findings were first presented in May 2026 at the World Congress for Hair Research in Seoul before this peer-reviewed publication. NewNew Peer-Reviewed Study Published in Dermatology and Therapy Adds to Clinical Evidence Showing Nutrafol Hair Growth Nutraceuticals Improve Hair Growth in WomenJul 15, 2026

The landscape

The hair-thinning nutraceutical and topical field is populated almost entirely by other consumer supplement and device programs rather than mechanism-differentiated drug candidates: competitors identified in the same indication include Xtressé's gummy and nutraceutical supplements, Nutra Harmony's biotin-collagen-keratin complex, Revision Skincare's scalp serum, and Viviscal's oral supplement, none of which share a common validated mechanism with Nutrafol's formulation. No competitor trial in this set was found eligible as a head-to-head comparator to this study. Against a field with no disease-modifying drug therapy established for hair thinning, the informative bar for any single-arm nutraceutical result is whether the growth-rate gain holds up against an active comparator or placebo, not merely against a participant's own starting point.

Trial status

The underlying registry entry for NCT06376409 shows the trial moved to Completed status on July 3, 2025, with enrollment adjusted from 180 to 181 and the primary completion date shifted two days, from June 16 to June 18, 2025. That enrollment change is within the routine band the operational risk model uses to flag shifts, which requires a move of 20% or more before treating it as a signal, so the one-participant adjustment does not meet that threshold. NCT06376409Prospective Study of Nutraceutical Supplements to Support Hair Growth in FemalesNCT06376409

This analysis was produced using AI-assisted reporting systems, AppliedXL data, and official public records. These systems undergo editorial review, quality checks, and regular audits by human experts. Errors may still occur, as with any automated system. Always consult the linked primary sources. Read our AI Editorial Policy.